abstract：BACKGROUND:Nickel is a common allergen. OBJECTIVE:To examine the epidemiology of nickel sensitivity in North America. METHODS:Retrospective, cross-sectional analysis of 44,097 patients patch tested by the North American Contact Dermatitis Group from 1994 to 2014. Nickel sensitivity was defined as a positive patch tes...

journal_title：Journal of the American Academy of Dermatology

authors： Warshaw EM,Zhang AJ,DeKoven JG,Maibach HI,Belsito DV,Sasseville D,Fowler JF Jr,Fransway AF,Mathias T,Pratt MD,Marks JG Jr,Zug KA,Zirwas MJ,Taylor JS,DeLeo VA

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:The prognosis of drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is highly unpredictable. Severe complications, either related or unrelated to cytomegalovirus (CMV) reactivation, are a highly probable cause of death. OBJECTIVES:The aim was to estab...

journal_title：Journal of the American Academy of Dermatology

authors： Mizukawa Y,Hirahara K,Kano Y,Shiohara T

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Melanoma patients with negative nodes after sentinel lymph node biopsy are a heterogeneous group. Current guidelines fail to adequately stratify surveillance and treatment for this group. Also, there is scarce data on adjuvant treatments for these patients. OBJECTIVE:To create a nomogram including clinical ...

journal_title：Journal of the American Academy of Dermatology

authors： Bertolli E,de Macedo MP,Calsavara VF,Pinto CAL,Duprat Neto JP

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Alcohol consumption and smoking have long been suspected of increasing the risk of developing psoriasis. Most evidence to date has derived from cross-sectional or case-control studies. OBJECTIVE:We sought to investigate the effects of alcohol and smoking on incident psoriasis. METHODS:Alcohol consumption, ...

journal_title：Journal of the American Academy of Dermatology

authors： Dai YX,Wang SC,Chou YJ,Chang YT,Chen TJ,Li CP,Wu CY

更新日期：2019-03-01 00:00:00

abstract：:Multiple studies have shown that dermoscopy increases the sensitivity and specificity for the detection of skin cancers compared with examination by the naked eye. Dermoscopy can also lead to the detection of thinner and smaller cancers. In addition, dermoscopy leads to the more precise selection of lesions requiring ...

journal_title：Journal of the American Academy of Dermatology

authors： Yélamos O,Braun RP,Liopyris K,Wolner ZJ,Kerl K,Gerami P,Marghoob AA

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:There is large variability in the risk of sentinel lymph node (SLN) positivity among patients with intermediate thickness melanoma (ITM), with a subgroup of patients exhibiting a low risk of nodal disease. OBJECTIVE:To identify a group of patients with ITM for whom the risk of nodal disease is low. METHODS...

journal_title：Journal of the American Academy of Dermatology

authors： Hanna AN,Sinnamon AJ,Roses RE,Kelz RR,Elder DE,Xu X,Pockaj BA,Zager JS,Fraker DL,Karakousis GC

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Skin pigmentation disorders in systemic sclerosis (SSc) have been sparsely described in the literature. Nevertheless, they could be a diagnostic and/or severity marker. OBJECTIVES:To assess the association between pigmentation disorders and systemic involvement in patients with SSc. METHODS:A total of 5 pa...

journal_title：Journal of the American Academy of Dermatology

authors： Leroy V,Henrot P,Barnetche T,Cario M,Darrigade AS,Manicki P,Doutre MS,Lazaro E,Constans J,Barcat D,Vernhes JP,Richez C,Taieb A,Truchetet ME,Seneschal J,Fédération Hospitalo-Universitaire–Aquitaine's Care and Research Organi

更新日期：2019-02-01 00:00:00

abstract：:As the most common human cancer worldwide and continuing to increase in incidence, basal cell carcinoma is associated with significant morbidity and cost. Continued advances in research have refined both our insight and approach to this seemingly ubiquitous disease. This 2-part continuing medical education article wil...

journal_title：Journal of the American Academy of Dermatology

authors： Cameron MC,Lee E,Hibler BP,Barker CA,Mori S,Cordova M,Nehal KS,Rossi AM

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Safe and efficacious topical treatments are needed for atopic dermatitis (AD). OBJECTIVE:We assessed the safety and efficacy of tapinarof cream (2 concentrations and 2 application frequencies) in patients with AD. METHODS:A double-blind, vehicle-controlled, randomized, 6-arm trial (1:1:1:1:1:1) in patients...

journal_title：Journal of the American Academy of Dermatology

authors： Peppers J,Paller AS,Maeda-Chubachi T,Wu S,Robbins K,Gallagher K,Kraus JE

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Biologics targeting interleukin 17A (IL-17A) allow for rapid clearance of psoriatic plaques, with a clinically favorable safety profile. OBJECTIVES:To compare the safety and efficacy of ixekizumab, an IL-17A antagonist, with the safety and efficacy of the IL-12/23 inhibitor ustekinumab through 52 weeks of t...

journal_title：Journal of the American Academy of Dermatology

authors： Paul C,Griffiths CEM,van de Kerkhof PCM,Puig L,Dutronc Y,Henneges C,Dossenbach M,Hollister K,Reich K

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The optimal long-term dosing strategy for adalimumab (ADA) in hidradenitis suppurativa/acne inversa (HS) was evaluated by pooling the results of the PIONEER phase 3 trials and an open-label extension (OLE) study. OBJECTIVE:To assess the response to and tolerability of long-term administration of ADA in HS. ...

journal_title：Journal of the American Academy of Dermatology

authors： Zouboulis CC,Okun MM,Prens EP,Gniadecki R,Foley PA,Lynde C,Weisman J,Gu Y,Williams DA,Jemec GBE

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Wide-ranging prevalence estimates of psoriatic arthritis (PsA) in patients with psoriasis have been reported. OBJECTIVES:To assess the prevalence and incidence of PsA in patients with psoriasis. METHODS:Two authors independently searched 3 databases for studies reporting on the prevalence or incidence of P...

journal_title：Journal of the American Academy of Dermatology

authors： Alinaghi F,Calov M,Kristensen LE,Gladman DD,Coates LC,Jullien D,Gottlieb AB,Gisondi P,Wu JJ,Thyssen JP,Egeberg A

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Methotrexate has been used both as monotherapy and as an adjunct to corticosteroids in the treatment of alopecia areata (AA), though there exists a paucity of definitive evidence and guidelines in this setting. OBJECTIVES:To 1) determine the efficacy and risks associated with methotrexate therapy for AA, 2)...

journal_title：Journal of the American Academy of Dermatology

authors： Phan K,Ramachandran V,Sebaratnam DF

更新日期：2019-01-01 00:00:00

abstract：:Neutrophilic dermatoses are a heterogeneous group of inflammatory skin disorders that present with unique clinical features but are unified by the presence of a sterile, predominantly neutrophilic infiltrate on histopathology. The morphology of cutaneous lesions associated with these disorders is heterogeneous, which ...

journal_title：Journal of the American Academy of Dermatology

authors： Nelson CA,Stephen S,Ashchyan HJ,James WD,Micheletti RG,Rosenbach M

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic potential. Wide local excision (WLE) and Mohs micrographic surgery (MMS) are common treatments, although no consensus exists regarding optimal therapy. OBJECTIVE:To systematically review e...

journal_title：Journal of the American Academy of Dermatology

authors： Tolkachjov SN,Kelley BF,Alahdab F,Erwin PJ,Brewer JD

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:The incidence of melanoma is rising faster than that of any other preventable cancer in the United States. The American Academy of Dermatology has sponsored free skin cancer education and screenings conducted by volunteer dermatologists in the United States since 1985. OBJECTIVE:We aimed to assess the Ameri...

journal_title：Journal of the American Academy of Dermatology

authors： Okhovat JP,Beaulieu D,Tsao H,Halpern AC,Michaud DS,Shaykevich S,Geller AC

更新日期：2018-11-01 00:00:00

abstract：:Sjögren syndrome (SS) is an autoimmune connective tissue disorder (CTD) that principally affects the lacrimal and salivary glands. Although SS is 1 of the 3 most common autoimmune CTDs alongside systemic lupus erythematosus and progressive systemic sclerosis, it is the least researched CTD overall. SS poses a particul...

journal_title：Journal of the American Academy of Dermatology

authors： Jhorar P,Torre K,Lu J

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Early specialist evaluation during rapid proliferative growth of complicated infantile hemangiomas (IH) is crucial. Health disparities and barriers of access-to-care for children with IH have not been examined. OBJECTIVE:Investigate whether socioeconomic status (SES) is associated with age at subspecialist ...

journal_title：Journal of the American Academy of Dermatology

authors： Lie E,Psoter KJ,Püttgen KB

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Genetic and environmental risk factors have been associated with the development of multiple primary melanomas (MPM). We hypothesized that individuals with MPM may have increased predisposition to developing internal malignancies. OBJECTIVE:To identify the risk of subsequent malignancies in MPM patients. M...

journal_title：Journal of the American Academy of Dermatology

authors： Cai ED,Swetter SM,Sarin KY

更新日期：2018-10-01 00:00:00

abstract：:In addition to being recognized as a chronic inflammatory disease that manifests in the skin, psoriasis is increasingly understood to be a systemic disease that causes immune dysregulation throughout the body. The systemic nature of psoriasis is evidenced by the higher burden of comorbidities and shorter life expectan...

journal_title：Journal of the American Academy of Dermatology

authors： Lockshin B,Balagula Y,Merola JF

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The appropriate classification of study designs is important for review and assessment of the relevant scientific literature as a basis for decision making; however, little is known about whether study designs have been appropriately reported in the dermatology literature. OBJECTIVE:We aimed to validate the...

journal_title：Journal of the American Academy of Dermatology

authors： Ohn J,Eun SJ,Kim DY,Park HS,Cho S,Yoon HS

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Noninvasive fat removal is preferred because of decreased downtime and lower perceived risk. It is important to seek new noninvasive fat removal treatments that are both safe and efficacious. OBJECTIVE:To assess the extent to which carboxytherapy, which is the insufflation of carbon dioxide gas into subcuta...

journal_title：Journal of the American Academy of Dermatology

authors： Alam M,Sadhwani D,Geisler A,Aslam I,Makin IRS,Schlessinger DI,Disphanurat W,Pongprutthipan M,Voravutinon N,Weil A,Chen BR,West DP,Veledar E,Poon E

更新日期：2018-08-01 00:00:00

abstract：:The second article in this continuing medical education series discusses cosmetic practices associated with cultural dermatoses, including hair care, traditional clothing, and skin decorations. Often, the steps individuals take to enhance their physical appearance are determined by cultural perceptions of beauty. With...

journal_title：Journal of the American Academy of Dermatology

authors： Vashi NA,Patzelt N,Wirya S,Maymone MBC,Kundu RV

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Rituximab (RTX) is an effective therapy for patients with pemphigus; however, the therapy does not prevent relapse. OBJECTIVES:To compare early relapsing patients (before 12 months) and late relapsing patients (after 24 months) following RTX therapy. METHOD:In this prospective study, 19 patients were enrol...

journal_title：Journal of the American Academy of Dermatology

authors： Saleh MA

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Few studies have evaluated the relationship between hidradenitis suppurativa (HS) and type 2 diabetes mellitus (T2DM), and the existing data show conflicting results. OBJECTIVE:To determine the prevalence of T2DM among patients with HS and identify at-risk demographic subgroups. METHODS:Cross-sectional ana...

journal_title：Journal of the American Academy of Dermatology

authors： Garg A,Birabaharan M,Strunk A

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Mycoplasma pneumoniae infection has been documented in erythema multiforme (EM) and Stevens-Johnson syndrome-toxic epidermal necrosis (SJS-TEN). Clinical aspects of M pneumoniae-related EM have been poorly described in the literature. OBJECTIVE:To highlight differences between M pneumoniae EM and non-M pneu...

journal_title：Journal of the American Academy of Dermatology

authors： Amode R,Ingen-Housz-Oro S,Ortonne N,Bounfour T,Pereyre S,Schlemmer F,Bequignon E,Royer G,Wolkenstein P,Chosidow O

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:The association of nonparaneoplastic pemphigus with comorbid hematologic malignancies has yet to be established. OBJECTIVE:To estimate the association between pemphigus and the common types of hematologic malignancies. METHODS:A cross-sectional study was conducted comparing pemphigus patients with age-, se...

journal_title：Journal of the American Academy of Dermatology

authors： Kridin K,Zelber-Sagi S,Comaneshter D,Batat E,Cohen AD

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Extramammary Paget disease (EMPD) sometimes shows an ill-defined border and an unexpectedly extended tumor spread beyond the clinical borders. Mapping biopsy is 1 approach for complete surgical removal, but its efficacy has remained controversial. OBJECTIVE:We sought to evaluate mapping biopsies for EMPD. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kaku-Ito Y,Ito T,Tsuji G,Nakahara T,Hagihara A,Furue M,Uchi H

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Mouse studies show that tumor-derived prostaglandins and platelets promote melanoma progression and immune evasion. OBJECTIVE:Determine whether aspirin confers longer survival in patients with melanoma. METHODS:A retrospective cohort study of 1522 patients at Indiana University Health who had melanoma diag...

journal_title：Journal of the American Academy of Dermatology

authors： Rachidi S,Wallace K,Li H,Lautenschlaeger T,Li Z

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Digital dermoscopic image analysis of pigmented skin lesions (PSLs) has become increasingly popular, despite its unclear clinical utility. Unbiased, high-powered studies investigating the efficacy of commercially available systems are limited. OBJECTIVE:To investigate the diagnostic performance of the FotoF...

journal_title：Journal of the American Academy of Dermatology

authors： Del Rosario F,Farahi JM,Drendel J,Buntinx-Krieg T,Caravaglio J,Domozych R,Chapman S,Braunberger T,Dellavalle RP,Norris DA,Fathi R,Alkousakis T

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Bullous pemphigoid is an autoimmune disease that typically presents with tense bullae and severe pruritus. However, bullae can be lacking, a subtype termed nonbullous pemphigoid. OBJECTIVE:To summarize the reported characteristics of nonbullous pemphigoid. METHODS:The EMBASE and MEDLINE databases were sear...

journal_title：Journal of the American Academy of Dermatology

authors： Lamberts A,Meijer JM,Jonkman MF

更新日期：2018-05-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is a disorder of myeloid neoplasia of dendritic cells that affects 1 in 200,000 children <15 years of age and even fewer adults. LCH presents with a spectrum of clinical manifestations. High-risk stratification is reserved for infiltration of blood, spleen, liver, and lungs. After d...

journal_title：Journal of the American Academy of Dermatology

authors： Tran G,Huynh TN,Paller AS

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:A wide array of miscellaneous agents is being studied for the treatment of atopic dermatitis (AD), including targeted topical, oral systemic, and biologic agents. OBJECTIVE:To review the known efficacy and safety to date for such agents being studied for the treatment of AD. METHODS:A nonsystematic review ...

journal_title：Journal of the American Academy of Dermatology

authors： Vakharia PP,Silverberg JI

更新日期：2018-03-01 00:00:00

abstract：:In 2002, the National Rosacea Society assembled an expert committee to develop the first standard classification of rosacea. This original classification was intended to be updated as scientific knowledge and clinical experience increased. Over the last 15 years, significant new insights into rosacea's pathogenesis an...

journal_title：Journal of the American Academy of Dermatology

authors： Gallo RL,Granstein RD,Kang S,Mannis M,Steinhoff M,Tan J,Thiboutot D

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Eczema is a common chronic inflammatory disease of the skin. Studies suggest differences in disease prevalence and severity by race/ethnicity. Our knowledge of health care utilization for eczema among different racial/ethnic groups remains limited. OBJECTIVE:To evaluate health care utilization for childhood...

journal_title：Journal of the American Academy of Dermatology

authors： Fischer AH,Shin DB,Margolis DJ,Takeshita J

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Genital or vulval lichen planus (VLP) may have a disabling effect on a patient's quality of life. Evidence-based management guidelines are lacking for VLP. OBJECTIVE:We sought to review clinical presentation and treatment of patients who received a diagnosis of VLP. METHODS:The 100 consecutive patients who...

journal_title：Journal of the American Academy of Dermatology

authors： Fahy CMR,Torgerson RR,Davis MDP

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The impact of dermatology consultation on the care of children with oncologic conditions is unknown. OBJECTIVE:To review outpatient dermatology visits and the resulting impact on diagnosis and management of pediatric oncology patients. METHOD:Retrospective review of pediatric oncology patients with outpati...

journal_title：Journal of the American Academy of Dermatology

authors： Song H,Robinson SN,Huang JT

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:The epidemiology of pediatric melanoma is distinct from that seen in adults. This is more distinguishable when pediatric patients are separated into prepubertal and adolescent groups. OBJECTIVE:In this study, we compared epidemiologic, clinical, histologic, and molecular characteristics of pediatric superfi...

journal_title：Journal of the American Academy of Dermatology

authors： Verzì AE,Bubley JA,Haugh AM,Zhang B,Wagner A,Kruse L,West DP,Wayne J,Guitart J,Gerami P

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:The American Academy of Dermatology (AAD) practice profile surveys have been conducted for more than a decade to gauge trends in our workforce supply and demand. OBJECTIVE:To update the trends and current workforce issues for the field of dermatology. METHODS:The AAD Practice Profile Survey is sent by both...

journal_title：Journal of the American Academy of Dermatology

authors： Ehrlich A,Kostecki J,Olkaba H

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Despite recommendations to limit the use of oral antibiotics and increasing support for hormonal agents in the treatment of acne, it is unclear whether there have been any significant changes in practice patterns. OBJECTIVE:To characterize changes in prescribing behavior for systemic agents in the treatment...

journal_title：Journal of the American Academy of Dermatology

authors： Barbieri JS,James WD,Margolis DJ

更新日期：2017-09-01 00:00:00